A Mutationdes CCR5 gene protects against HIV / AIDS in Germany live 800,000 people who have inherited the gene of resistance against HIV/AIDS by both parents. These people are largely immune to HIV/AIDS. Keep up on the field with thought-provoking pieces from Reshma Kewalramani. This resistance is the mutation of the CCR5 gene in the human genome. How does the resistance come from? HI viruses need a receptor to enter the cell and infect them. In most cases, this receptor is a protein on the surface of so-called macrophages and lymphocytes (immune cells of the people), the CCR5 “protein. Individuals that a mutation, called Delta 32 deletion bear, produce a modified CCR5 protein that HIV viruses; do not use as a receptor therefore does not usually to the infection, because the key”of HIV viruses not in the door lock fits.

“The cause of this HIV resistance, mutation of the gene CCR5 (” CCR5 polymorphism “) in the human genome, has after previous state of research during the of the black death rampant in Central Europe” emerged. Its unknown Germ that flooded Europe in the middle ages in several waves, has killed 25 million people and depopulated whole tracts of land. Individuals with this mutation had to have had a significant survival benefit. The presence of the mutation has no disease value for the carrier and it is not a sick making mutation, but rather a genetic immunity. It shows no faulty gene so on, but on the contrary a protective gene, which conveys innate immunity against HIV and AIDS. The CCR5 test makes it clear that if a person wears this resistance gene. The German laboratory testing service offers this test for anyone interested. This test is interesting, all persons who have an infection risk. Working people who live with an HIV-positive partner, in the hospital, in the care sector, the police, in the correctional facility or other social institutions. Rainer Hubner

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